VMware vSphere
This issue occurs because the RDM LUN is not visible on the target host.
If the RDM LUN is visible, but it does not always present to the target host, you may see the error:
Virtual Disk 'X' is a mapped direct access LUN that is not accessible
ESXi host takes a long time to start during rescan of RDM LUNs
vMotion fails at 20% for MSCS/Microsoft WSFC VMs with RDM disks
Confirming ESX/ESXi host hardware (System, Storage, and I/O) compatibility
Performing a rescan of the storage on an ESX/ESXi host
Migrating virtual machines with Raw Device Mappings (RDMs)
Powering on or migrating a virtual machine fails with the error: Virtual Disk 'X' is a mapped direct access LUN that is not accessible
Cannot see some or all storage devices in VMware vCenter Server or VirtualCenter