With two separate vCenter Servers in place, a potential exists to create duplicate MAC addresses for the virtual machines. This is expected behavior for two vCenter Servers, however if these two environments are connected to the same Physical Switch, there will be a conflict.
Each vCenter Server system has a vCenter Server instance ID. This ID is a number between 0 and 63 that is randomly generated at installation time, but can be reconfigured after installation. vCenter Server uses the instance ID to generate MAC addresses and UUIDs for virtual machines. If two vCenter Server systems have the same vCenter Server instance ID, they might generate identical MAC addresses (duplicate MAC address) for virtual machines. This can cause conflicts if the virtual machines are on the same network, leading to packet loss and other problems.