VMware vCenter Server 4.x and 5.0 require that the database and ADAM (VMwareVCMSDS) data be backed up.
Note: The ADAM data is backed up every 5 minutes into the vCenter Server database. To back up the latest update of ADAM data, ensure that the VMware VirtualCenter Management Webservices service has been running for at least 5 minutes before stopping the other vCenter Server services.
This requires a procedure similar to upgrading vCenter Server 2.5 to vCenter Server 4.x or from vCenter Server 4.x to 5.0.
%ALLUSERSPROFILE%\Application Data\VMware\VMware VirtualCenter
%ALLUSERSPROFILE%\VMWare\VMware VirtualCenter
rui.crt
file, ensure that the file starts with -----BEGIN CERTIFICATE-----
and ends with -----END CERTIFICATE-----
Note: On vSphere 5.0 you should also back up the Inventory Service database as part of your regular vCenter Server database administration.