When CICS Vector Table module (DBCVTPR) is re-assembled and re-linked, recycling CICS region is always the quickest and safest way to refresh it. This is the suggested method.
However, there is a way to accomplish this without shutting down CICS.
Here are the steps required to refresh CVT when CICS is active:
In case the DBOC STARTUP doesn't autoconnect to the MUF regions, a DBEC CONNECT must be executed.