The connectivity from ESX hosts to the iSCSI array
The MTU settings for the vSwitch and VMNICs
Check the duplex settings on the vSwitch, Physical Switch and iSCSI SAN and make sure they are same across the board
Note:
This issue is seen to occur on Juniper switches. On some Juniper switches, the default MTU is 1514. This issue may occur if the MTU for the connected port is set to a value other than 1514. Changing the port MTU back to 1514 resolves this issue. For more information, see Configuring the Media MTU section of the JUNOS 8.4 Network Interfaces Configuration Guide or contact Juniper support.
The preceding link was correct as of February 28, 2010. If you find the link is broken, provide feedback and a VMware employee will update the link.
This issue also occurs when using the DELL switch Power connect 8024. You experience this issue when the MTU of the switch and the vSwitch on the ESX host are both set to 9000. To resolve this issue, the switch should be configured with a MTU more than the MTU configured on the ESX host.