This is a known issue affecting the Cb Defense Sensor 3.0.x.x and MS Office Applications
Resolution
This is resolved in the 3.1.x, 3.2.1.51, 3.3.x, 3.4.0.1016 and 3.5.x Sensors and Higher please upgrade to resolve the issue
If the issue is being observed in 3.6+, please see https://community.carbonblack.com/t5/Knowledge-Base/Carbon-Black-Cloud-TMP-Files-Left-Behind-After-Closing-MS-Excel/ta-p/104259
Additional Information
Note: A related issue for 3.4.0.1047 can be found here: https://community.carbonblack.com/t5/Knowledge-Base/CB-Defense-Microsoft-Office-Applications-Freeze-or-Crash-with/ta-p/77885