Most of your emails are being delivered successfully, but some messages are queueing in O365, and they appear to be rejected by DLP Cloud Service. The errors may vary, but will likely include the following errors:
421 4.3.0 Fatal: Processing error. Closing connection.
451 4.4.4 Mail received as unauthenticated, incoming to a recipient domain configured in a hosted tenant which has no mail-enabled subscriptions. ATTR5
451 4.4.62 Mail sent to the wrong Office 365 region. ATTR35. For more information please go to https://go.microsoft.com/fwlink/?linkid=865268
550 5.7.64 TenantAttribution; Relay Access Denied
Again, the above errors are only happening for a small subset of emails being sent - the majority of messages are being delivered without any errors. If queued emails in O365 are for messages with "null senders", such as OOOs, auto-forwarded messages or NDRs, then you will need to make the below, additional change to your O365 configuration.
DLP Cloud Service for Email - customers in "O365 Reflecting mode" only
The "Inbound Connector" for DLP in your O365 Tenant needs to be set so that the "subject name on the certificate" for the DLP Detector matches the "accepted domain" for our service.
The DLP Inbound Connector as configured in O365 must be configured with a subject name that matches an accepted domain in O365.
Therefore, you need to modify the entry for "By verifying that the subject name on the certificate that the sending server uses to authenticate with Microsoft 365 matches this domain name."
Login to O365 and edit your existing Inbound Connector for DLP. Complete instructions on doing both of these steps are here:
Configuring Microsoft 365 to use Microsoft 365 for Email Delivery (Reflecting mode)
1234567a-abcd-efgh-ijkl-12345678abcd.ds.dlp.protect.broadcom.com12345678-abcd-efgh-ijkl-12345678abcd
12345678-abcd.ds.dlp.protect.broadcom.com12345678-abcd.ds.dlp.protect.broadcom.comThe above change should not have any negative impacts on current mailflow. It will, however, allow any queued emails with "null sender" values to be delivered successfully.
For more complete information on these changes, with details on the exact steps to take, review the following topics: