Outbound Emails from O365 rejected by Symantec Email.Cloud with the error:
Reason: [453-you are trying to use me [server-X.tower-X.messagelab X-s.com] as a relay, but I have not been configured to let you [{*}X.X.X.X{*}, mail-X.outbound.protection.outlook.com] do this. Please visit https://knowledge.broadcom.com/external/article?legacyId=TECH246726 for more details about this error message and instructions to resolve this issue. (#4.7.1)
Symantec Email Security.Cloud
This issue is happening because one of these conditions:
1- Microsoft Office 365 isn't listed as a Hosted Email Services in the Outbound Routes page.
2- The envelope sender domain isn't listed in the Domains page.
In order to resolve this issue, make sure to have the following:
1- Add " Microsoft Office 365 " as a Hosted Email Services in the Outbound Routes page
2- Add your domain " envelope sender address " to the Domain page. Please check this tech document for further details on adding new domains.
Note: If you are adding any of the *.onmicrosoft.com subdomains, then make sure to create a TXT record for the domain in the Microsoft 365 Admin Center.