We need to block clipboard actions (copy and paste) through Web Isolation.
Release : 1.16
To Block Copy
Under Profiles > Application Data protection > Uncheck/Disable "Copy" under Permissions > clipboard
This is what you will see on Browser
Can be verified in Activity logs as below
To Block Paste
Under Profiles > End-User Data Protection > Uncheck/Disable "Paste" under Permissions > clipboard
Once Disabled, When try Ctrl+V on Isolated site, You will see below on browser
You can validate same in Activity Logs
Note: The website requires to be Isolated for Copy/Paste Block to work , Also correct Profiles needs to be applied to Rules for it to match correctly.