Multiple Package server fail to download the Packages as they are attempting to save to a drive that does not exist on the server. In this case they were all trying to download to the F: drive.
Release : 8.x
Unknown, but most likely an F: drive existed at some point. Based on that we can say pretty sure that the issue is caused by the "drive rotation" feature.
In this case, the agent installation drive has enough disk space for all expected packages in the Package Delivery folder of the Altiris Agent.