When SEP clients are configured to upload quarantine files to the Symantec Endpoint Protection, the upload will fail if the files quarantined were inside an archive file ( ie zip files )
This issue is fixed in SEP 14.3 RU6, in this version the SEPM will request the archive file itself to be uploaded from the client's quarantine. This requires both the client and the SEPM to be on 14.3 RU6 or higher.