You wish to know whether or not you can configure EDR in an environment that uses a proxy server.
All versions of Symantec EDR 4.x
A network proxy is installed and configured between Symantec EDR and the internet.
Symantec EDR is not able to use a DNS server over proxy. EDR does not support the use of DNS proxy on HTTPS. It is not a supported configuration for EDR.
Please verify that your environment uses a proxy server in one of the following ways.
A 'network proxy' is the proxy that exists between EDR and Symantec servers. The network proxy is configured on an EDR management appliance. This is so that EDR knows a proxy is being used when establishing communication with Symantec servers (i.e. license registration and liveupdate). See Configuring network proxy information in the EDR documentation
The 'enterprise proxy' is a configuration related to SEDR (ATP) Network Scanner functionality. This is used to tell where the proxy server exists in a network topology when the scanner is configured for inspecting network traffic. See Building an enterprise proxy list in the EDR documentation