The Certificate Management page shows the following warning:
"Non-selfsigned certificate detected in Trusted Root Certificate Authorities certificate store. There can be problems with CEM Agent connections to NS"
ITMS 8.x
The Trusted Root Certification Authorities store on the Notification Server has one or more certificates where "Issued By" and "Issued To" don't match. This indicates that the certificate was issued by a certificate authority other than itself.
For additional information and reference see the following Microsoft article: Non-self-signed certificates are in Trusted Root Certification Authorities Certificate store