This article documents a known issue where within specific MCS configuration profiles, clicking within the white space of a profile can enable or disable options.
An example of this issue can be seen with the Default Disk(s) Enhanced Monitoring Profile:
Release : 20.3
Component : UIM OPERATOR CONSOLE - MCS UI
UIM 20.3.3 July Patch
Engineering has confirmed this issue will be addressed in the upcoming monthly patch release (ETA 7th - 10th Sept).