After enabling the Windows Defender Co-Exist option in the Virus and Spyware policy, clients start seeing a large number of WS.Reputation.1 detections on non-executable files.
The Co-Exist option incorrectly triggers the SEP client to perform reputation lookups on file types that we do not support reputation for resulting in them being detected as WS.Reputation.1 incorrectly.
14.3 RU1 / 14.3 RU1 MP1
Windows Defender Co-Exist option is enabled
For 14.3 RU1 and 14.3 RU1 MP1, disable the Windows Defender Co-exist option in the Virus and Spyware policy.
The Windows Defender Co-exist option is no longer available as of 14.3 RU2.