When releasing an email from quarantine in Mail Security for Microsoft Exchange (SMSMSE), you get an error similar to:
There was an error with the following item(s)
This is most commonly caused by a lack of permissions when releasing mail from quarantine. Because of how Windows UAC, it is common for applications to run without administrative privileges even if the launching user is an administrator.
Launch the console explicitly as administrator by Right Click -> Run as Administrator.
You can configure the console to always launch as administrator by doing the following: