The release notes for Symantec Endpoint Detection and Response (SEDR) 4.6 are available here: https://techdocs.broadcom.com/content/dam/broadcom/techdocs/symantec-security-software/endpoint-security-and-management/endpoint-detection-and-response/generated-pdfs/sedr_release_notes_4.6.pdf
New issues discovered after the 4.6 release will be listed here.