A public hot fix to provide Chrome 75 support is available from the My Products tab of MySymantec.
The hot fix addresses issues a problem in which file uploads using Chrome 75 were not monitored for files uploaded using the File Open dialog box. This issue was described in the Support article, "Chrome 75 Windows monitoring partially broken for Symantec Data Loss Prevention Endpoint."
To install the hot fix, download Hotfix_15.5.0107.01001_b.zip from MySymantec and follow the instructions provided in the readme file that accompanies the hot fix.
NOTE: A separate hot fix for Data Loss Prevention 15.1 MP2 is available at MySymantec. See this Alert for details.