Trying to upgrade to windows from 1709 to 1809 with DLP agent installed the upgrade fails
You see errors in the install log such as
Cannot write security information for registry key HKLM\SYSTEM\CurrentControlSet\services\EDPA (error 0x00000005)[gle=0x000003f0]
Error [0x080782] MIG CRegistryDataStore::Create: Failed to set reflection key flags for HKLM\SYSTEM\CurrentControlSet\services\EDPA[gle=0x00000005]
Error [0x080789] MIG CRegistryDataStore::Create: Failed to set LUA key flags for HKLM\SYSTEM\CurrentControlSet\services\EDPA[gle=0x00000005]
Error SP Error WRITE, 0x00000005 while gathering/applying object: Registry, HKLM\SYSTEM\CurrentControlSet\services\EDPA . Will return 0
Error MIG Error 5 while applying object HKLM\SYSTEM\CurrentControlSet\services\EDPA . Shell application requested abort
Error [0x08097b] MIG Abandoning apply due to error for object: HKLM\SYSTEM\CurrentControlSet\services\EDPA 
Error Apply failed. Last error: 0x00000000
Windows installer cannot update registry keys that are in use and locked by the EDPA agent.
Permissions issue the service must have Local Admin privileges.
If using SCCM be aware that service level, may or may not have the appropriate permissions.
There are several possible resolutions.
Microsoft is aware of the issue, but as of the time of this article does not know why the permission settings are not being set correctly.