The Intelligent Updater (IU) provided by Symantec Security Response for the Symantec Scan Engine 5.2 product does not run on a 64-bit operating system.
When Intelligent Updater for Symantec Scan Engine (SSE) is executed, it will report that it is incompatible with a 64-bit version OS.
Symantec's Security Response currently does not provide a 64-bit version of the Intelligent Updater compatible with Symantec Scan Engine. IU's are available for 32-bit platform and Unix platforms.
One possible procedure to update the definitions:
An additional workaround would be to setup an internal LiveUpdate Administrator 2.x server, and configure SSE's LiveUpdate client to retrieve virus definitions from this LUA 2.x server.
An enhancement request (Connect Forum "Idea") has been proposed for an IU that updates 64-bit SSE. For more details, and to express your opinion for or against such a product, please visit the Intelligent Updater Needed for 64-Bit Scan Engine entry in Connect, Symantec's peer-support forums.