You would like to enable TLS on a Messaging Gateway, but do not have a certificate from a Certificate Authority and would like to use a self-signed certificate instead.
Per the Administration guide for version 10.6 (pg 182):
A self-signed certificate can be used for either HTTPS communication or SMTP/TLS. A self-signed certificate used for SMTP/TLS may not be recognized by some email servers. Many email servers require a certificate authority-signed certificate. A self-signed certificate is not recommended for SMTP/TLS.