Could ITMS benefit from the caching of http.sys and registry settings found in the HKLM\SYSTEM\CurrentControlSet\Services\HTTP\Parameters?
Navigate to the registry to find the following settings:
HKLM\SYSTEM\CurrentControlSet\Services\HTTP\Parameters\
"URIEnableCache"
"UriMaxUriBytes"
"UriScavengerPeriod"
ITMS 8.x
The settings are not configured for "URIEnableCache", "UriMaxUriBytes" and "UriScavengerPeriod" by default.
These values are related to the http.sys driver kernel mode cache for responses. By default they do not exist in the registry which means that the default values are used (cache is enabled by default). You can read more about this cache here for example:
Working with HTTP.SYS or Kernel Mode Caching in Internet Information Services 6.0 (it's the same for newer server versions also)
ITMS does not rely on this cache and does not try to modify these values to check the overall influence on behavior to the Notification Server. Performance can be affected but it is unlikely that you can get significant increase by changing them. Most requestsesponses are personalized for calling the Sym Agent, so it's unknown exactly how ITMS might benefit from this cache. This however it is required for proper operation.