The Symantec Management Agent requires enough free disk space available to download policies and save credentials.
ITMS 8.x
If the disk is full there is no way that storage can be modified without a "dirty mark" file modification which requires a few bytes. Seems that more general solutions with some disk reservation for emergency cases is needed.
Workaround is to use a local ACC account and to free up some disk space by doing the following:
lease refer to KB article How the 'Re-enable the created local account if it has been locked out' setting works