Symantec Advanced Threat Protection (ATP) 3.x and Symantec Endpoint Detection Response (SEDR) 4.x virtual edition (VE) require VM resources to be reserved for that VM alone.
By default, the ATP 3.x/SEDR 4.x OVA allocates 48GB of RAM and 12 CPUs. To reserve the VM resources, you will need to edit the VM guest and specify the amount of resources to reserve.
Note: The vSphere/ESXI host must have these resources physically available and not reserved by any other VMs in order to allocate to the ATP VM. If you do not have enough physical resources for the VM, the VM will be in an unsupported configuration and may not function correctly.
NOTE: If the block size is not set correctly the EDR appliance will need to be reinstalled when the datastore is re-deployed with the correct block size. See Block size limitations of a VMFS datastore (1003565) - https://kb.vmware.com/s/article/1003565