All users from one location attempting to access a website are receiving:
Network Error: A communication error occurred: "Connection Refused" on one data pod.
Other locations connecting to different data centers or data pods are able to reach the website.
A communication error occurred:
This Web Server may be down, too busy, or experiencing other problems preventing it from responding to requests. You may wish to try again at later time.
The website could be blocking the data center egress IPs.
Bring it to the attention of Symantec Support to confirm https://support.symantec.com/us/en/mysymantec.html
Provide the data center you are connected to when receiving the error.
Navigate to pod.threatpulse.com, select more.
If possible, supply a screen-shot of the above page to Symantec.