Endpoint Protection clients fails to connect to the Endpoint Protection Manager over HTTPS with the following error "Security certificate error (12045)".
The Server Connection Status under Help - Troubleshooting reports "Security certificate error (12045)".
10/03 13:25:03.985  <SendRegistrationRequest:>https://SEPM:443
10/03 13:25:04.079  Unable to confirm HTTPS connection by public key or trusted root.
10/03 13:25:04.375  CInternetException: <SendRegistrationRequest:>: The certificate authority is invalid or incorrect
This can occur if a proxy or firewall is interfering with the traffic between SEPM and the client.
Bypass any potential proxy or disable SSL inspection to rule out any interference.