Symantec Endpoint Protection Manager (SEPM) login returns ErrorCode 0x10010000. Clicking the Home, Monitors or Reports tab returns a blank page.
An ODBC connection test fails to connect to the Microsoft SQL Server: https://support.symantec.com/en_US/article.TECH160964.html
Symantec Endpoint Protection Manager (SEPM) login
ODBC connection test
ODBC is failing to establish an SSL connection to the SQL Server.
SEPM 12.1 does not support an encrypted connection to the SQL Server: https://support.symantec.com/en_US/article.TECH178558.html
Support for an encrypted connection to the SQL Server was added in SEPM 14.0: https://support.symantec.com/en_US/article.HOWTO125362.html
Documentation of relevant SQL Server and ODBC settings: https://support.microsoft.com/en-us/help/316898/how-to-enable-ssl-encryption-for-an-instance-of-sql-server-by-using-mi