After upgrading from 14.x to 14.6 or above you would like to use domain accounts instead of local administrator accounts 

The following steps will switch a local account to a domain account:

1. Stop the Vontu services on the Windows Server.
2. Change the account tied to each service to the new domain account.
3. Give the domain acount Full Control over the Symantec DLP dIrectory and any Drop_* folders (located at the root of the installation drive).
4. Start the Vontu services