Endpoint agents report in Enforce with a Warning status. Looking at the agent in Enforce, it reports "Active Directory user group resolution failed." When looking at the agent logs from an affected machine, you note that the agent is attempting to do an Active Directory lookup for the NT Authority\SYSTEM account.
05/21/2017 07:17:58 | 18272 | INFO | AgentServices.UserGroupResolver | Group resolution failed for user [NT AUTHORITY\SYSTEM]. | [OS ERROR 8250] The server is not operational.
This issue is resolved in DLP 14.6 MP2.