When applying the rule Disable SSL Detection from within the VPM you are simply disabling the detection of SSL encrypted traffic over a non-standard port. The Edge SWG (ProxySG) will still attempt to detect other protocols.
For example:
<proxy>url.domain=example.com detect_protocol (none)
<proxy>url.address=#.#.#.# detect_protocol (none)
Not all applications report a User-Agent so this may not be an option for all scenarios.
<proxy>User-Agent="application-specific-agent-name" detect_protocol (none)
If you have multiple URLs, IP addresses, or User-Agents that require this rule, or if you would like to learn more about the detect_protocol property, please refer to the Content Language Policy Guide. It provides detailed instructions on how to create "Condition" rules to encompass multiple objects within a single rule.
.