SSL interception can be disabled for a single URL/Domain using CPL or VPM policy if the deployment is explicit. In a transparent deployment, SSL can be disabled using server certificate and not destination URL as mentioned in How to bypass SSL based on server certificate.
This will not disturb SSL interception for other URLs or Domains.
Resolution
Disable SSL interception through the VPM:
Log in to the Management Console (https://<IP_address>:8082).
There is an "Install policy" section where you can install policy from a local file, forward file, and central file.
Select Text Editor from the drop-down list to the right of "Install Local file from". Click Install.
If this is a new proxy deployment, your local policy may be blank. If this is an established proxy with local policy, scroll down to the bottom of the data contained in the text editor.
Copy and paste the following CPL to disable SSL interception for the site that you want to bypass from SSL interception. In this case, we'll use www.example.com in the rule: