When attempting to uncheck the box, located at Settings > All Settings > Software > Software Portal Settings > Software Portal Settings, called "publish software across all domains" you receive and error that you are unable to do so because a piece of software is being published to a domain that is outside the NS's domain.
Publishing software across all domains can significanlty increase load times of the portal resulting in 2 errors:
"HTTP request failed" and "/Altiris/SoftwarePortal/UserPortal/Home.aspx. Request Timed Out."
In addition to load times causing portal time outs when you attempt to uncheck the box to publish software across all domains you also recieve a message that one or more softwares have been published outside the domain of the NS. As a result you are unable to uncheck the box to resolve the load times.
SMP 8.0 HF2
This will change the value so it is no longer checked.
IMPORTANT: After importing the XML do not click "save" at the bottom of the "Software Portal Settings" page.