When you launch Microsoft Internet Explorer (iexplore.exe), one or more events appear in the Symantec Endpoint Protection (SEP) 12.1 Tamper Protection Log.
The Tamper Protection Log details are as follows:
Actor: C:\Program Files (x86)\Internet Explorer\iexplore.exe
Target: C:\ProgramData\Symantec\Symantec Endpoint Protection\<CurrentVersion>\Data\Definitions\IPSDefs\<Installed Definitions Version>\IPSEng32.dll
AND
Target: C:\ProgramData\Symantec\Symantec Endpoint Protection\<CurrentVersion>\Data\Definitions\IPSDefs\<Installed Definition Version>\IPSLdr32.dll
Microsoft App-V version 5.0 SP2 or later is installed on the machine, and Dynamic Virtualization is enabled. When you launch Internet Explorer, Microsoft App-V generates Tamper Protection log entries in SEP 12.1 because it reads one or more SEP 12.1 .DLL files.
The following independent solutions/workarounds are available: