This article addresses the file processing size limits of Data Loss Prevention.
Based on the default settings, a Detection Server will only process message content that is 30 MB or smaller.
One exception to this is with encapsulation formats (.zip, .z, .tar, .rar etc). In that case, DLP will extract the files and process them.
The 30MB value can be increased, but there can be resource issues for increasing the size.
Large files not detected on the Endpoint
Large Files not Detected on the Server: