File Path Filtering only works for Local Drive and Application File Monitoring. It does not work for CD/DVD.
There are two eTracks to make the Agent configuration more intuitive.
Etrack-3054863 - Detections requests are not generated for CD/DVD activity if file path filter is applied to the CD/DVD monitoring channel
Etrack-3061814 - Enforce Pre-Filter UI needs to me more Intuitive.