This article details the email clients supported with PGP Desktop 10.2.1 for Mac OS X.
When secure email messaging is enabled, PGP Desktop monitors the email traffic between your email client and your mail server. Depending on the circumstances, PGP Desktop will intercede on your behalf to encrypt, sign, decrypt, or verify messages.
Compatible Email Client Software
PGP Desktop 10.2.1 MP5 for Mac OS X will, in most cases, work without problems with any Internet-standards-based email client that runs on Mac OS X 10.5.x or Mac OS X 10.6.x.