Are Deployment Solution (DS) jobs / tasks possible when using a Cloud-enabled Management (CEM) configuration?  If clients are connected through the supported CEM site server and in CEM mode, will DS jobs and tasks work?

No. Though workarounds may be possible in some environments to enable this functionality, they have not been tested, are not recommended, and cannot be supported.

While tasks will work in CEM configurations, immediate execution of those tasks will not because the task agent can not bind to the task server to be awakened whenever a task is available. Thus, "immediate" task execution is disabled, and the time out period for tasks executing in the cloud may have to be significantly increased.

Additionally, DS jobs frequently "map a drive" for the tasks to function, and this is not possible in the cloud.