This article describes some instability issues between the PGP Desktop client software and Microsoft Application Virtualization 4.5 or 4.6.
The following are errors that have been observed on systems with this incompatibility between PGP Desktop and MS App-V:
Could not start the Application Virtualization Client service on Local Computer.
System instability issues could also occur ranging from the MS App-V client not launching properly, errors reported for MS App-V in logging and BSOD issues.
PGP Desktop 10.2.1 MP3 and above has been tested and works properly with MS App-V 4.6 SP1 (188.8.131.523). Older PGP Desktop client versions are not recommended, due to some other observed incompatibility issues. To allow Microsoft App-V client and PGP Desktop to work on the same system, installing the MS App-V version 4.6 SP1 client before installing the PGP Desktop software may be necessary.
Windows XP SP3 x86, Windows 7 SP1 32-bit, and Windows 7 64-bit.
Based on current findings, the system does not need to be encrypted with PGP Whole Disk Encryption to encounter these issues with versions prior to MS App-V 4.6 SP1.