The ESM modules for Oracle database are used to assess the security of Oracle Databases 10g R1, 10g R2, 11G R1, and 11G R2.

http://www.symantec.com/avcenter/security/ESM/AM/2011.12.06/InstallationGuide.pdf
 

Table 1-4 Supported operating systems for ESM modules on Oracle

10.1.0.x,
10.2.0.x,
11.1.0.6.0,
11.2.0.1.0

Having said that, you might have version 11.2.0.3  and the release notes claim both "11G R2" and at the same time "11.2.0.1.0" - you want to know if point release of Oracle are supported.

Symantec Enterprise Security Manager - Symantec™ Enterprise Security Manager Modules for Oracle Databases version 5.1 supports 10g R1, 10g R2, 11G R1, and 11G R2 and this includes point releases like 11.2.0.3.

Applies To

Symantec Enterprise Security Manager - Symantec™ Enterprise Security Manager Modules for Oracle Databases version 5.1