When accessing the Symantec Endpoint Protection Manager web console, the ip address displayed in the server field is always an address in 169.254.x.x
APIPA is typically not used on managed networks, it is best practice to disable unused Network Interfaces.
Windows will configure an APIPA address if a Network Interface is connected to a physical network and the NIC is configured to use DHCP but no DHCP server was available.
Assign a fixed ip address or disable the network interfaces using an APIPA IP address.
The server on which the SEPM is installed has several network cards and one or more is using an APIPA address in 169.254.x.x.