The Operation Status when trying to deploy Virus Definitions to a group shows "Waiting for response from server(s)" and does not change.
Steps to deploy Virus Definitions to a group:
You find the following entry in your Application Event log:
SMSMSE uses ASP.NET to transfer the package from the client console to the server. The ASP.NET configuration used by SMSMSE runs out of memory while trying to transfer such large packages.
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This will run LiveUpdate locally on that sever. You can monitor the status under "Status of On-demand Update."