Symantec Drive Encryption 10.3.2 as well as Symantec Endpoint Encryption 11 (SEE 11) supports most typical hardware available in systems and in general, no issues are seen.
Recently, some systems which have NVMe drives have been found to be incompatible with Symantec Drive Encryption 10.3.2 and Symantec Endpoint Encryption 11 and encrypting these systems can result in Blue Screen behavior, as well as potentially unbootable systems.
The following models are known to be affected by this issue:
Dell XPS 13 950 & 9350
Dell XPS 15 9550
Dell Inspiron E7470
HP Folio G1 EliteBook
Surface Pro 4 (See article TECH233421 for more information on this system).
MSI GS60 6QE Ghost Pro
UPDATE May 6 2016: Symantec has developed a fix for this issue and is available in Symantec Endpoint Encryption 11.1.1, which is available via fileconnect.
UPDATE APRIL 26 2016: Symantec has developed a fix for this issue and is available in 3.3.2/10.3.2 MP13, which is available via fileconnect.
Although this issue is resolved in Symantec Drive Encryption 10.3.2 MP13 and SEE 11.1.1, there are a few considerations to review:
Once the above considerations have been met, the system should boot properly after it is encrypted with Symantec Drive Encryption 10.3.2 MP13 or SEE 11.1.1. If the problems persist, please work with Symantec Support to resolve the issue.
3875901 - Symantec Endpoint Encryption 11.0.1 on a HP Z440
3885162 - Symantec Endpoint Encryption 11.0.1 and 11.1 on Dell XPS 13 950
3900056 - Symantec Endpoint Encryption 11.1 on MSI GS60 6QE Ghost Pro
3883315 - Symantec Drive Encryption 10.3.2MP11 on Dell XPS 13 950, Dell XPS 13 9350, & Dell Precision Tower 3620
3884273 - Symantec Drive Encryption 10.3.2MP11 on HP zBook
3874204 - Symantec Drive Encryption 10.3.2MP11 on Surface Pro 4 and Surface Book
Symantec Drive Encryption 10.3.2 MP12 was released to includes fixes to the NVMe systems, however this build was pulled due to an issue found. For more information on this issue, see article ALERT2011 (now fixed in 10.3.2 MP13).