The MQ + button on the MQ Asset is disabled (grey'ed out).
There were ENV Variables set that was pointing to other mq jars and this was interfering the all-client jars for Lisa and was not loaded properly by Workstation.
Release : 10.4
Component : CA Service Virtualization
MQ Systme Variables were added to the ENV variables for other MQ application, and were pointing to other MQ jars.
Add LISA_POST_CLASSPATH =pathto/all-client.jar specifically for DEVTEST
This should resolve the issue.