PTF QO61321 to resolve the '4228I VSAM OPEN ERROR' contains nothing in the PTF and will not apply.
What do you advise?
Please RECEIVE and APPLY PTF RO40830 as it replaces the QO61321 PTF and fixes the error you are now reporting.
It is available under Support Online for the product, CA Easytrieve Report Generator - VSE 6.3:
RO40830: 0102:VSE 4228I VSAM OPEN ERROR X'80'(128)